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Oct 23, 2026
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CHEM 2090 - Biochemistry
Credits: 3
Catalog Description
This is a one semester non-biochemistry major course designed for students majoring in the biological sciences or preparing for careers in the health sciences such as pharmacy, medicine, veterinary, and chiropractic. Topics include a review of aqueous chemistry, bonding, and thermodynamics; structure and function of biological macromolecules (proteins, lipids, carbohydrates, and nucleic acids); enzyme catalysis; metabolic pathways (structures, enzymes, and energetics); and the chemical foundation of genetic information. Three lecture hours per week.
Prerequisite(s) (must have a grade of C or better): CHEM 2061 and BIOL 1106
Recommended Skills, Abilities, or Coursework: CHEM 2062
Additional fee to student: No
Learner Outcomes
- Describe the structures and functions of the major classes of biomolecules (proteins, lipids, carbohydrates, and nucleic acids).
- Describe and analyze the precursors, biosynthetic pathways, and metabolic pathways of the major classes of biomolecules.
- Describe and analyze the molecular structures, enzymes, processes, and energetics involved in key metabolic pathways.
- Describe and analyze the molecular structures, enzymes, and processes involved in the transduction, transcription, and translation of genetic information.
- Apply standard reaction mechanisms common to many biomolecular reactions.
- Analyze kinetics and equilibria of biochemical systems to determine pH, buffer behavior, functional group protonation, and enzyme kinetics.
- Describe and apply modern quantitative methods used in experimental biochemistry.
Major Areas of Course Content
- Aqueous Chemistry Review
- Chemical bonding
- Acid-base reactions
- pH, pK, buffers, and the Henderson-Hasselbalch equation
- Biomolecules
- Amino Acids and Proteins
- Peptide bonds
- Acid-base properties and titration
- Charge
- Protein structure
- Experimental analysis
- Enzymes
- Energetics of catalysis
- Kinetics, Michaelis-Menten equation
- Catalytic active site
- Carbohydrates
- Classification
- Stereochemistry and conformation
- Polysaccharide structure and function
- Glycoproteins
- Lipids and Membranes
- Fatty acids
- Triacylglycerols
- Glycerophospholipids
- Sphingolipids
- Cholesterol
- Membrane fluidity, structures, functions
- Transmembrane proteins
- Nucleic acids
- Chemical structure and base composition
- DNA/RNA structure, function
- Metabolism
- Metabolic kinetics, equilibrium, energetics
- Transfer and storage of cellular energy
- Glycolysis structures and enzymes
- Gluconeogenesis and Glycogen Metabolism
- Isoenzymes and catabolism
- Regulation
- Citric Acid Cycle
- Electron Transport and Oxidative Phosphorylation
- ATP and electron flow
- Coenzymes
- Pentose Phosphate Pathway and NADPH
- Lipid Metabolism
- Protein Metabolism
- Photosynthesis
- Molecular Biology
- Central dogma of molecular biology
- DNA Biosynthesis and Replication
- RNA Synthesis/Transcription
- Protein Synthesis/Translation
- Recombinant DNA and DNA Sequencing
Credit for Prior Learning Options
No credit for prior learning option is available for this course.
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